Opportunity Information: Apply for RFA RM 15 017
The NIH Common Fund is inviting applications for a research initiative focused on generating a comprehensive knockout mouse resource. This program aims to systematically produce and phenotype null-mutant mouse lines for each gene in the C57BL/6 strain to better understand mammalian gene function. Using CRISPR/Cas9 technology, researchers will create approximately 600 mutant mouse lines per year, totaling 3,000 over five years.
The project includes generating mutant lines, conducting phenotyping assays, ensuring quality control, cryopreserving germplasm, and making both the mice and data widely available to the scientific community. Mice are considered an ideal model for this large-scale functional genomics effort due to their well-established genetics, rapid reproduction, and relatively low cost.
Only U.S.-based organizations are eligible to apply. While foreign components may be involved as defined in NIH policy, non-U.S. entities and non-U.S. components of American organizations cannot serve as primary applicants.Apply for RFA RM 15 017
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Limited Competition: Knockout Mouse Production and Phenotyping Project (UM1)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.233, 93.273, 93.279, 93.310, 93.313, 93.351, 93.396, 93.837, 93.838, 93.839, 93.846, 93.847, 93.853, 93.855, 93.856, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2015-10-07.
- Applicants must submit their applications by 2015-12-09. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
- Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education.
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